Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.56 extracted from

  • Goswami, B.B.; Crea, R.; Van Boom, J.H.; Sharma, O.K.
    2-5-Linked oligo(adenylic acid) and its analogs. A new class of inhibitors of mRNA methylation (1982), J. Biol. Chem., 257, 6867-6870.
    View publication on PubMed
Search for more literature for 2.1.1.56

Inhibitors

Inhibitors Comment Organism Structure
additional information 2'-AMP, 3'-AMP Mus musculus
additional information 2'-AMP, 3'-AMP Vaccinia virus
Oligoadenylic acid mono- and triphosphates 2'-5'-linked, with varying numbers of phosphate groups, methylated in the 3'-terminal hydroxy group or all three 3'-hydroxy groups, different types of inhibition of viral and L-cell enzyme Mus musculus
Oligoadenylic acid mono- and triphosphates 2'-5'-linked, with varying numbers of phosphate groups, methylated in the 3'-terminal hydroxy group or all three 3'-hydroxy groups, different types of inhibition of viral and L-cell enzyme Vaccinia virus

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
-
 Vaccinia virus 19013
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 L929-cells
-
Vaccinia virus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Vaccinia virus

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA
-
 Mus musculus S-adenosyl-L-homocysteine + m7G(5')pppR-RNA R may be guanosine or adenosine, mRNA containing an N7-methylguanine cap ?
S-adenosyl-L-methionine + G(5')pppR-RNA
-
 Vaccinia virus S-adenosyl-L-homocysteine + m7G(5')pppR-RNA R may be guanosine or adenosine, mRNA containing an N7-methylguanine cap ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mus musculus
37
-
 assay at Vaccinia virus