Literature summary for 2.1.1.55 extracted from

Golovina, A.Y.; Sergiev, P.V.; Golovin, A.V.; Serebryakova, M.V.; Demina, I.; Govorun, V.M.; Dontsova, O.A.
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC) (2009), RNA, 15, 1134-1141.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli AG1 cells	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	strains BW25141 and JW2559	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA agarose column chromatography	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + adenine 37 in tRNA1Val(cmo5UAC)	the enzyme specifically methylates adenosine at position 37 of tRNA1Val(cmo5UAC)	Escherichia coli	S-adenosyl-L-homocysteine + N6-methyladenine 37 in tRNA1Val(cmo5UAC)	-	?

Synonyms

Synonyms	Comment	Organism
adenine-N6 methyltransferase	-	Escherichia coli
YfiC protein	-	Escherichia coli

General Information

General Information	Comment	Organism
physiological function	the yfiC gene confers a growth advantage under conditions of osmotic and oxidative stress	Escherichia coli

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Release 2023.1 (January 2023)