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Literature summary for 2.1.1.4 extracted from
- Species heterogeneity of pineal hydroxyindole-O-methyltransferase (1983), J. Neurochem., 40, 790-796.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 39000 | - |
2 * 39000, SDS-PAGE | Gallus gallus |
| 39000 | - |
2 * 39000, SDS-PAGE | Bos taurus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Gallus gallus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Gallus gallus |
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pineal gland | - |
Gallus gallus | - |
| pineal gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| bufotenine + S-adenosyl-L-methionine | - |
Gallus gallus | S-adenosyl-L-homocysteine + N,N-dimethyl-5-hydroxytryptamine | - |
? |  |
| bufotenine + S-adenosyl-L-methionine | - |
Bos taurus | S-adenosyl-L-homocysteine + N,N-dimethyl-5-hydroxytryptamine | - |
? | |
| additional information | bovine enzyme has high specificity towards N-acetylserotonin, chicken enzyme methylates N-acetylserotonin and to some extent serotonin and bufotenine | Gallus gallus | ? | - |
? | |
| additional information | bovine enzyme has high specificity towards N-acetylserotonin, chicken enzyme methylates N-acetylserotonin and to some extent serotonin and bufotenine | Bos taurus | ? | - |
? | |
| S-adenosyl-L-methionine + N-acetylserotonin | - |
Gallus gallus | S-adenosyl-L-homocysteine + N-acetyl-5-methoxytryptamine | - |
? | |
| S-adenosyl-L-methionine + N-acetylserotonin | - |
Bos taurus | S-adenosyl-L-homocysteine + N-acetyl-5-methoxytryptamine | - |
? | |
| serotonin + S-adenosyl-L-methionine | - |
Gallus gallus | S-adenosyl-L-homocysteine + 5-methoxytryptamine | - |
? | |
| serotonin + S-adenosyl-L-methionine | - |
Bos taurus | S-adenosyl-L-homocysteine + 5-methoxytryptamine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 39000, SDS-PAGE | Gallus gallus |
| dimer | 2 * 39000, SDS-PAGE | Bos taurus |
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Release 2023.1 (January 2023)
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