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Literature summary for 2.1.1.382 extracted from

  • Naidu, D.; Ragsdale, S.
    Characterization of a three-component vanillate O-demethylase from Moorella thermoacetica (2001), J. Bacteriol., 183, 3276-3281 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.382

Inhibitors

Inhibitors Comment Organism Structure
O2
-
 Moorella thermoacetica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.083
-
 vanillate pH 6.6, 55°C Moorella thermoacetica
9
-
 dicamba pH 6.6, 55°C Moorella thermoacetica

Metals/Ions

Metals/Ions Comment Organism Structure
Co(I) reaction involves Co(I), and is O2 sensitive Moorella thermoacetica

Organism

Organism UniProt Comment Textmining
Moorella thermoacetica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dicamba + [Co(I) methoxylated corrinoid protein MtvC]
-
 Moorella thermoacetica a [methyl-Co(III) methoxylated corrinoid protein MtvC] + 3,6-dichloro-2-hydroxybenzoate
-
 ?
vanillate + [Co(I) methoxylated corrinoid protein MtvC]
-
 Moorella thermoacetica a [methyl-Co(III) methoxylated corrinoid protein MtvC] + 3,4-dihydroxybenzoate
-
 ?

Subunits

Subunits Comment Organism
? x * 48000, SDS-PAGE Moorella thermoacetica

Synonyms

Synonyms Comment Organism
mtvB
-
 Moorella thermoacetica

Cofactor

Cofactor Comment Organism Structure
tetrahydrofolate required as the acceptor of the methyl group from vanillate, Km value 0.23 mM Moorella thermoacetica

General Information

General Information Comment Organism
physiological function MtvB is part of an inducible three-component aromatic O-demethylase system. MtvB catalyzes methyl transfer from a phenylmethylether to the cobalt center of MtvC, a corrinoid protein. All three protein components are required for O-demethylase activity Moorella thermoacetica