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Literature summary for 2.1.1.369 extracted from

  • Jacob, Y.; Stroud, H.; Leblanc, C.; Feng, S.; Zhuo, L.; Caro, E.; Hassel, C.; Gutierrez, C.; Michaels, S.D.; Jacobsen, S.E.
    Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases (2010), Nature, 466, 987-991 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8VZJ1
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Arabidopsis thaliana Q9FNE9
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Synonyms

Synonyms Comment Organism
ARABIDOPSIS TRITHORAX-RELATED PROTEIN5
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Arabidopsis thaliana
ARABIDOPSIS TRITHORAX-RELATED PROTEIN6
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Arabidopsis thaliana
ATXR5
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Arabidopsis thaliana
Atxr6
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Arabidopsis thaliana
SET15
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Arabidopsis thaliana
SET34
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function mutation of isoforms ATXR5 and ATXR6 lead to rereplication of specific genomic locations, the vast majority of which correspond to transposons and other repetitive and silent elements of the Arabidopsis genome. These sites also correspond to high levels of H3K27 monomethylation. Mutation of ATXR5 and ATXR6 also causes upregulation of transposon expression and has pleiotropic effects on plant development Arabidopsis thaliana
physiological function mutation of isoforms ATXR5 and ATXR6 lead to rereplication of specific genomic locations, the vast majority of which correspond to transposons and other repetitive and silent elements of the Arabidopsis genome. These sites also correspond to high levels of H3K27 monomethylation. Mutation of ATXR5 and ATXR6 also causes upregulation of transposon expression and has pleiotropic effects on plant development. The PIP motif, PHD and SET domains are all required for ATXR6 activity Arabidopsis thaliana