Literature summary for 2.1.1.369 extracted from

Ma, Z.; Castillo-Gonzalez, C.; Wang, Z.; Sun, D.; Hu, X.; Shen, X.; Potok, M.E.; Zhang, X.
Arabidopsis serrate coordinates histone methyltransferases ATXR5/6 and RNA processing factor RDR6 to regulate transposon expression (2018), Dev. Cell, 45, 769-784.e6 .

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Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q8VZJ1	-	-
Arabidopsis thaliana	Q9FNE9	isoform Atxr6	-

General Information

General Information	Comment	Organism
physiological function	isoforms ATXR5 and ATXR6 interact with RNA metabolism component serrate. Serrate binds to ATXR5/6-regulated transposable elements loci and promotes H3K27me1 accumulation in these regions. Serrate directly enhances ATXR5 enzymatic activity in vitro. Serrate mutation suppresses the transposable elements reactivation and DNA rereplication phenotypes in the Atxr5/Atxr6 mutant through RDR6	Arabidopsis thaliana

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Release 2023.1 (January 2023)