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Literature summary for 2.1.1.366 extracted from

  • Rapone, R.; Del Maestro, L.; Bouyioukos, C.; Albini, S.; Cruz-Tapias, P.; Joliot, V.; Cosson, B.; Ait-Si-Ali, S.
    The cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for embryonic stem cells (2023), iScience, 26, 107386.
    View publication on PubMed
Search for more literature for 2.1.1.366

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Mus musculus 5737
-
nucleus
-
 Mus musculus 5634
-

Organism

Organism UniProt Comment Textmining
Mus musculus O88974
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryonic stem cell
-
 Mus musculus
-

Synonyms

Synonyms Comment Organism
histone lysine
-
 Mus musculus
methyltransferase Setdb1
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for survival of embryonic stem cells. Setdb1 interacts with many RNA-binding proteins and translation regulators such as Trim71. Setdb1 is required for Trim71 complex integrity cSetdb1 regulates the abundance of specific mRNAs, of which Trim71 and hnRNPc targets Mus musculus