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Literature summary for 2.1.1.366 extracted from
- CBX7 inhibitors affect H3K9 methyltransferase-regulated gene repression in leukemic cells (2024), Exp. Hematol., 142, 104691.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q15047 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leukemia cell | - |
Homo sapiens | - |
| OCI-AML3 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| H3K9 methyltransferase | - |
Homo sapiens |
| SETDB1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | CBX7 inhibition reduces H3K9 methylation levels. CBX7 inhibitors abolish the interaction between CBX7 and H3K9 methyltransferases and block both CBX7-and H3K9 methyltransferase-mediated gene repression | Homo sapiens |
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Release 2026.1 (March 2026)
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