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Literature summary for 2.1.1.364 extracted from

  • Zhang, X.; Bruice, T.C.
    Enzymatic mechanism and product specificity of SET-domain protein lysine methyltransferases (2008), Proc. Natl. Acad. Sci. USA, 105, 5728-5732.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
Y245F the mutation converts the enzyme from a mono- to a dimethyltransferase Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K4) SET7/9 only catalyzes the transfer of one methyl group to the target lysine Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
histone lysine methyltransferase
-
Homo sapiens
SET-domain protein lysine methyltransferase
-
Homo sapiens
SET7/9
-
Homo sapiens