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Literature summary for 2.1.1.364 extracted from

  • Mai, A.; Cheng, D.; Bedford, M.T.; Valente, S.; Nebbioso, A.; Perrone, A.; Brosch, G.; Sbardella, G.; De Bellis, F.; Miceli, M.; Altucci, L.
    Epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors (2008), J. Med. Chem., 51, 2279-2290.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
eosin AMI-5, numerous different substitutes of eosin synthesized and tested for inhibition Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens modification of histone tails ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information modification of histone tails Homo sapiens ?
-
?
S-adenosyl-L-methionine + histone H3
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
histone lysine methyltransferase
-
Homo sapiens
HKMT
-
Homo sapiens
SET7
-
Homo sapiens