Application | Comment | Organism |
---|---|---|
analysis | multiple ab initio quantum mechanical/molecular mechanical free energy calculations and molecular dynamics simulations for the investigation of the methyl-transfer reaction catalyzed by SET7/9 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | methyl-transfer reaction catalyzed by SET7/9 is a typical in-line SN2 nucleophilic substitution reaction with a transition state of 70% dissociative character, transfers only one methyl group to the unmodified histone-lysine residue H3-K4 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
histone lysine methyltransferase SET7/9 | - |
Homo sapiens |