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Literature summary for 2.1.1.361 extracted from

  • Sakaguchi, A.; Karachentsev, D.; Seth-Pasricha, M.; Druzhinina, M.; Steward, R.
    Functional characterization of the Drosophila Hmt4-20/Suv4-20 histone methyltransferase (2008), Genetics, 179, 317-322 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + a [histone H4]-N6,N6-dimethyl-L-lysine20 Drosophila melanogaster
-
S-adenosyl-L-homocysteine + a [histone H4]-N6,N6,N6-trimethyl-L-lysine20
-
?
S-adenosyl-L-methionine + a [histone H4]-N6-methyl-L-lysine20 Drosophila melanogaster
-
S-adenosyl-L-homocysteine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q9W5E0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6,N6,N6-trimethyl-L-lysine20
-
?
S-adenosyl-L-methionine + a [histone H4]-N6-methyl-L-lysine20
-
Drosophila melanogaster S-adenosyl-L-homocysteine + a [histone H4]-N6,N6-dimethyl-L-lysine20
-
?

Synonyms

Synonyms Comment Organism
H4K20 di- and trimethyltransferase
-
Drosophila melanogaster
histone H4 lysine20 trimethyltransferase
-
Drosophila melanogaster
histone H4-K20 trimethyltransferase
-
Drosophila melanogaster
Hmt4-20
-
Drosophila melanogaster
Suv4-20
-
Drosophila melanogaster

General Information

General Information Comment Organism
physiological function the enzyme is not required for survival and does not control position-effect variegation Drosophila melanogaster