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Literature summary for 2.1.1.360 extracted from
- Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79 (2011), J. Biol. Chem., 286, 17530-17535.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + histone H3(K79) | - |
Saccharomyces cerevisiae | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Dot1 | - |
Saccharomyces cerevisiae |
| histone methyltransferase | - |
Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | Dot1 and histone H3(K79) methylation are required for global genomic repair in both nucleosomal core regions and internucleosomal linker DNA but the enzyme is entirely dispensable for transcription coupled repair | Saccharomyces cerevisiae |
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