Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Trypanosoma brucei Lister 427 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + histone H3(K76) | - |
Trypanosoma brucei | ? | - |
? | |
S-adenosyl-L-methionine + histone H3(K76) | - |
Trypanosoma brucei Lister 427 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DOT1B | - |
Trypanosoma brucei |
General Information | Comment | Organism |
---|---|---|
malfunction | transcriptionally silent telomeric variant surface glycoproteins become partially derepressed when DOT1B is deleted, whereas nontelomeric loci are unaffected | Trypanosoma brucei |
physiological function | DOT1B is required to maintain strict variant surface glycoproteins silencing and to ensure rapid transcriptional variant surface glycoproteins switching | Trypanosoma brucei |