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Literature summary for 2.1.1.359 extracted from

  • Wang, X.; Chen, J.; Xie, Z.; Liu, S.; Nolan, T.; Ye, H.; Zhang, M.; Guo, H.; Schnable, P.S.; Li, Z.; Yin, Y.
    Histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression in Arabidopsis thaliana (2014), Mol. Plant, 7, 1303-1315.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q2LAE1
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K36)
-
Arabidopsis thaliana S-adenosyl-L-homocysteine + histone H3(K36) N6-methyl-L-lysine di- and trimethylation of resdídue K36 ?

Synonyms

Synonyms Comment Organism
ASHH2
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Arabidopsis thaliana
SDG8
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function histone lysine methyltransferase SDG8 is involved in brassinosteroid-regulated gene expression. Transcription factor BES1 interacts with SDG8, directly or indirectly through IWS1, a transcription elongation factor involved in brassinosteroid-regulated gene expression. The knockout mutant sdg8 displays a reduced growth phenotype with compromised brassinosteroid responses. While brassinosteroids regulate about 5000 genes in wild-type plants, the hormone regulates fewer than 700 genes in SDG8 mutant. More than half of brassinosteroid-regulated genes are differentially affected in SDG8 mutant Arabidopsis thaliana