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Literature summary for 2.1.1.355 extracted from
- SETDB1 plays an essential role in maintenance of gonocyte survival in pigs (2017), Reproduction, 154, 23-34 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | SETDB1 localizes strongly in cytoplasm | Sus scrofa | 5737 | - |
| nucleus | SETDB1 localizes weakly in nuclei in GFRA1-positive spermatogonia | Sus scrofa | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | F1SS95 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| germ | - |
Sus scrofa | - |
| gonocyte | SETDB1 is strongly localized in gonocytes | Sus scrofa | - |
| testis | SETDB1 expression gradually increases during testis development | Sus scrofa | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SETDB1 | - |
Sus scrofa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | knockdown of SETDB1 gene expression leads to gonocyte apoptosis and a decrease in H3K27me3, but no significant change in H3K9me3 | Sus scrofa |
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Release 2023.1 (January 2023)
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