Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Drosophila melanogaster | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
180000 | - |
x * 180000, enzyme form dG9a, SDS-PAGE | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + histone H3(K9) | SETDB1 is mainly responsible for mono- and trimethylation of histone H3 lysine 9 and SU (VAR)3-9 for monomethylation of histone H3 lysine 9 during spermatogenesis | Drosophila melanogaster | S-adenosyl-L-homocysteine + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 180000, enzyme form dG9a, SDS-PAGE | Drosophila melanogaster |
Synonyms | Comment | Organism |
---|---|---|
dG9a | - |
Drosophila melanogaster |
H3K9-specific histone methyltransferase | - |
Drosophila melanogaster |
histone H3K9 methyltransferase | - |
Drosophila melanogaster |
HMTase | - |
Drosophila melanogaster |
SETDB1 | - |
Drosophila melanogaster |
SU (VAR)3-9 | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
physiological function | SETDB1 is mainly responsible for mono- and trimethylation of histone H3 lysine 9 and SU (VAR)3-9 for monomethylation of histone H3 lysine 9 during spermatogenesis. Enzyme form dG9a plays no apparent role for histone H3 lysine 9 methylation during spermatogenesis and spermiogenesis | Drosophila melanogaster |