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Literature summary for 2.1.1.354 extracted from

  • Soares, L.M.; He, P.C.; Chun, Y.; Suh, H.; Kim, T.; Buratowski, S.
    Determinants of histone H3K4 methylation patterns (2017), Mol. Cell, 68, 773-785.e6 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 Saccharomyces cerevisiae overall reaction 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine4 overall reaction Saccharomyces cerevisiae 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine4
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 ?
additional information fusing the enzyme to RNA polymerase II results in extended histone H3 lysine 4 methylation throughout the gene Saccharomyces cerevisiae ?
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Synonyms

Synonyms Comment Organism
COMPASS
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 Saccharomyces cerevisiae
SET1 catalytic subunit of COMPASS Saccharomyces cerevisiae