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Literature summary for 2.1.1.354 extracted from

  • Xu, Z.; Gong, Q.; Xia, B.; Groves, B.; Zimmermann, M.; Mugler, C.; Mu, D.; Matsumoto, B.; Seaman, M.; Ma, D.
    A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking (2009), J. Cell Biol., 186, 343-353.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome Dpy-30 functions in the endosome to trans-Golgi network transport of cation-independent mannose 6-phosphate receptor Rattus norvegicus 5768
-
nucleus
-
Rattus norvegicus 5634
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K4)
-
Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
Ash2L a subunit of histone H3 lysine 4 methyltransferase complexes Rattus norvegicus
Dpy-30 a subunit of histone H3 lysine 4 methyltransferase complexes Rattus norvegicus
H3K4 methyltransferase
-
Rattus norvegicus
H3K4MT
-
Rattus norvegicus
histone H3 lysine 4 methyltransferase
-
Rattus norvegicus
RbBP5 a subunit of histone H3 lysine 4 methyltransferase complexes Rattus norvegicus

General Information

General Information Comment Organism
physiological function Dpy-30 functions in the endosome to trans-Golgi network transport of cation-independent mannose 6-phosphate receptor, its knockdown results in the enrichment of internalized cation-independent mannose 6-phosphate receptor and recycling endosomes near cell protrusions. Dpy-30 and probably histone H3 lysine 4 methyltransferase play a role in the endosomal transport of specific cargo proteins Rattus norvegicus