Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Papaver somniferum |
Protein Variants | Comment | Organism |
---|---|---|
S122Y | profound negative effects on dimerization and activity | Papaver somniferum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine | Papaver somniferum | this activity is part of the noscapine biosynthesis pathway | S-adenosyl-L-homocysteine + 3-O-acetylpapaveroxine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Papaver somniferum | I3PLQ6 | I3PLQ6: 4'-O-desmethyl-3-O-acetylpapaveroxine O-methyltransferase subunit MT2, I3PLQ7: 4'-O-desmethyl-3-O-acetylpapaveroxine O-methyltransferase subunit MT3 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine | this activity is part of the noscapine biosynthesis pathway | Papaver somniferum | S-adenosyl-L-homocysteine + 3-O-acetylpapaveroxine | - |
? | |
S-adenosyl-L-methionine + 3-O-acetyl-4'-O-demethylpapaveroxine | 3-O-acetyl-4'-O-demethylpapaveroxine i.e. 6-[(S)-acetoxy[(5R)-4-hydroxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]-2,3-dimethoxybenzaldehyde. 3-O-Acetylpapaveroxine i.e. 6-[(S)-acetoxy[(5R)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]methyl]-2,3-dimethoxybenzaldehyde | Papaver somniferum | S-adenosyl-L-homocysteine + 3-O-acetylpapaveroxine | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | complex of the OMT2 gene product and the product of either OMT3 or 6OMT. OMT2 is the catalytic subunit in both complexes. 6OMT shares 81% amino acid sequence identity with OMT3 | Papaver somniferum |
General Information | Comment | Organism |
---|---|---|
metabolism | this activity is part of the noscapine biosynthesis pathway | Papaver somniferum |