Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8C3P7 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hippocampus | the abundance of METTL3 in wild-type mouse hippocampus is positively correlated with learning efficacy, and overexpression of METTL3 significantly enhances long-term memory consolidation | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
METTL3 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | depleting METTL3 in mouse hippocampus reduces memory consolidation ability, yet unimpaired learning outcomes can be achieved if adequate training is given or the m6A methyltransferase function of METTL3 is restored | Mus musculus |
physiological function | METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation | Mus musculus |