Literature summary for 2.1.1.348 extracted from

Wanna-Udom, S.; Terashima, M.; Lyu, H.; Ishimura, A.; Takino, T.; Sakari, M.; Tsukahara, T.; Suzuki, T.
The m6A methyltransferase METTL3 contributes to transforming growth factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB (2020), Biochem. Biophys. Res. Commun., 524, 150-155 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q86U44	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
A-549 cell	-	Homo sapiens	-
LC-2/ad cell	-	Homo sapiens	-
lung cancer cell line	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
METTL3	-	Homo sapiens

General Information

General Information	Comment	Organism
drug target	the enzyme (METTL3) contributes to transforming growth factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB. The significance of the regulation for m6A RNA modification in the important step of cancer progression provides the possibility to develop therapeutic strategies for the treatment of cancer metastasis	Homo sapiens
physiological function	the enzyme (METTL3) contributes to transforming growth factor-beta-induced epithelial-mesenchymal transition of lung cancer cells through the regulation of JUNB	Homo sapiens

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Release 2023.1 (January 2023)