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Literature summary for 2.1.1.328 extracted from

  • Du, Y.; Alkhalaf, L.; Ryan, K.
    In vitro reconstitution of indolmycin biosynthesis reveals the molecular basis of oxazolinone assembly (2015), Proc. Natl. Acad. Sci. USA, 112, 2717-2722.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + N-demethylindolmycin Streptomyces griseus subsp. griseus
-
S-adenosyl-L-homocysteine + indolmycin
-
?

Organism

Organism UniProt Comment Textmining
Streptomyces griseus subsp. griseus A0A0D4BSP3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + N-demethylindolmycin
-
Streptomyces griseus subsp. griseus S-adenosyl-L-homocysteine + indolmycin
-
?

Synonyms

Synonyms Comment Organism
ind7
-
Streptomyces griseus subsp. griseus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Streptomyces griseus subsp. griseus

General Information

General Information Comment Organism
physiological function methyltransferase Ind7 is responsible for the last N-methyltransfer reaction to generate indolmycin Streptomyces griseus subsp. griseus