Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Bay 11-7082 | inhibits the protein arginine methyltransferase 1 (PRMT1) activity in vitro, and treatment of cells with the inhibitor causes the decline of the levels of protein asymmetric dimethylarginine catalyzed by PRMT1 | Homo sapiens | |
Bay 11-7085 | inhibits the protein arginine methyltransferase 1 (PRMT1) activity in vitro, and treatment of cells with the inhibitor causes the decline of the levels of protein asymmetric dimethylarginine catalyzed by PRMT1 | Homo sapiens | |
phenyl vinyl sulfonate | inhibits the protein arginine methyltransferase 1 (PRMT1) activity in vitro, and treatment of cells with the inhibitor causes the decline of the levels of protein asymmetric dimethylarginine catalyzed by PRMT1 | Homo sapiens | |
phenyl vinyl sulfone | inhibits the protein arginine methyltransferase 1 (PRMT1) activity in vitro, and treatment of cells with the inhibitor causes the decline of the levels of protein asymmetric dimethylarginine catalyzed by PRMT1 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 S-adenosyl-L-methionine + [histone H4R3]-L-arginine | Homo sapiens | - |
2 S-adenosyl-L-homocysteine + [histone H4R3]-Nomega,Nomega-dimethyl-L-arginine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 S-adenosyl-L-methionine + [histone H4R3]-L-arginine | - |
Homo sapiens | 2 S-adenosyl-L-homocysteine + [histone H4R3]-Nomega,Nomega-dimethyl-L-arginine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PRMT1 | - |
Homo sapiens |
protein arginine methyltransferase 1 | - |
Homo sapiens |