Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4 S-adenosyl-L-methionine + 2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] | Drosophila sp. (in: flies) | post-translational modification of eukaryotic elongation factor 2 (eEF2) | 4 S-adenosyl-L-homocysteine + diphthine methyl ester-[translation elongation factor 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila sp. (in: flies) | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4 S-adenosyl-L-methionine + 2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] | - |
Drosophila sp. (in: flies) | 4 S-adenosyl-L-homocysteine + diphthine methyl ester-[translation elongation factor 2] | - |
? | |
4 S-adenosyl-L-methionine + 2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] | post-translational modification of eukaryotic elongation factor 2 (eEF2) | Drosophila sp. (in: flies) | 4 S-adenosyl-L-homocysteine + diphthine methyl ester-[translation elongation factor 2] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dph5 | - |
Drosophila sp. (in: flies) |
General Information | Comment | Organism |
---|---|---|
physiological function | Dph5 is required for gross translation activation and high dMyc protein level in RasV12 tumor-like hyperplasia. Dph5 is involved in the regulation of ribosome biogenesis genes. Diphthamidation is required for translation activation partly through the regulation of ribosome biogenesis in Ras-induced tumor-like hyperplasia model in Drosophila gut | Drosophila sp. (in: flies) |