Literature summary for 2.1.1.299 extracted from

Chen, D.; Dong, C.; Dong, G.; Srinivasan, K.; Min, J.; Noinaj, N.; Huang, R.
Probing the plasticity in the active site of protein N-terminal methyltransferase 1 using bisubstrate analogues (2020), J. Med. Chem., 63, 8419-8431.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	not inhibited by bisubstrates composed of (2S)-2-amino-4-({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}amino)butanoic acid and the peptide GPKRIA linked by a 4-C, 3-C, 4-C or 5-C atom linker	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q5VVY1	-	-

Synonyms

Synonyms	Comment	Organism
NTMT2	-	Homo sapiens
protein N-terminal methyltransferase 2	-	Homo sapiens

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Release 2026.1 (March 2026)