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Literature summary for 2.1.1.297 extracted from

  • Nie, D.S.; Liu, Y.B.; Lu, G.X.
    Cloning and primarily function study of two novel putative N5-glutamine methyltransferase (Hemk) splice variants from mouse stem cells (2009), Mol. Biol. Rep., 36, 2221-2228.
    View publication on PubMed
Search for more literature for 2.1.1.297

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus isoform HemK1 is detected mainly in the nucleus of COS7 cell lines after 24 h post-transfection Mus musculus 5634
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Organism

Organism UniProt Comment Textmining
Mus musculus Q6PRU9 isoform HemK2
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Mus musculus Q6SKR2 isoform HemK1
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Source Tissue

Source Tissue Comment Organism Textmining
brain abundant mRNA expression Mus musculus
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embryonic stem cell abundant mRNA expression in embryonic stem cells, weak expression in differentiated embryonic stem cells, proein is most abundant in undifferentiated embryonic stem cells Mus musculus
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embryonic stem cell abundant mRNA expression in embryonic stem cells, weak expression in differentiated embryonic stem cells, protein is most abundant in undifferentiated embryonic stem cells Mus musculus
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kidney weak mRNA expression Mus musculus
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additional information no expression in muscle, heart, placenta, pancreas, lung and stomach Mus musculus
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testis abundant mRNA expression Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no evidence for a DNA adenine-methyltransferase activity Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
HemK methyltransferase family member 2, isoform CRA_c
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 Mus musculus
Hemk1
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 Mus musculus
Hemk2
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 Mus musculus
N6AMT1
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 Mus musculus

General Information

General Information Comment Organism
physiological function the cell proliferation decreases after RNAi with Hemk1 Mus musculus