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Literature summary for 2.1.1.290 extracted from

  • Noma, A.; Kirino, Y.; Ikeuchi, Y.; Suzuki, T.
    Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA (2006), EMBO J., 25, 2142-2154.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.290

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Saccharomyces cerevisiae BY4742
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Purification (Commentary)

Purification (Comment) Organism
Ni+-chelating column chromatography Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme catalyzes methylation of the carboxyl group of the methionine moiety in wybutosine-72 to convert it to wybutosine-58. TYW4 is a bifunctional enzyme to synthesize wybutosine by catalyzing methylation and methoxycarbonylation of wybutosine -72 Saccharomyces cerevisiae ?
-
 ?
additional information the enzyme catalyzes methylation of the carboxyl group of the methionine moiety in wybutosine-72 to convert it to wybutosine-58. TYW4 is a bifunctional enzyme to synthesize wybutosine by catalyzing methylation and methoxycarbonylation of wybutosine -72 Saccharomyces cerevisiae BY4742 ?
-
 ?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine58 in tRNA
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 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + wybutosine58 in tRNA
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 ?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine58 in tRNA
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 Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + wybutosine58 in tRNA
-
 ?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine72 in tRNA
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 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + wybutosine72 in tRNAPhe
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 ?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine72 in tRNA
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 Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + wybutosine72 in tRNAPhe
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 ?

Synonyms

Synonyms Comment Organism
tRNA-yW synthesizing protein 4
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 Saccharomyces cerevisiae
TYW4
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 Saccharomyces cerevisiae
YOL141w
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 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
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 Saccharomyces cerevisiae