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Literature summary for 2.1.1.283 extracted from

  • Xue, Y.; Liang, Y.; Zhang, W.; Geng, C.; Feng, D.; Huang, X.; Dong, S.; Zhang, Y.; Sun, J.; Qi, F.; Lu, X.
    Characterization and structural analysis of emodin-O-methyltransferase from Aspergillus terreus (2022), J. Agric. Food Chem., 70, 5728-5737.
    View publication on PubMed
Search for more literature for 2.1.1.283

Application

Application Comment Organism
agriculture the enzyme may be used for the production of physcion or other site-specific O-methylated anthraquinone derivatives with potential applications as biopesticides Aspergillus terreus

Protein Variants

Protein Variants Comment Organism
Y173A/R343A the mutant produces questin plus 1-O-methylemodin from emodin Aspergillus terreus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
365800
-
 gel filtration Aspergillus terreus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + emodin Aspergillus terreus
-
 S-adenosyl-L-homocysteine + questin
-
 ?
S-adenosyl-L-methionine + emodin Aspergillus terreus NIH2624
-
 S-adenosyl-L-homocysteine + questin
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus terreus Q0CCY5
-
-
Aspergillus terreus NIH2624 Q0CCY5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + emodin
-
 Aspergillus terreus S-adenosyl-L-homocysteine + questin
-
 ?
S-adenosyl-L-methionine + emodin
-
 Aspergillus terreus NIH2624 S-adenosyl-L-homocysteine + questin
-
 ?

Subunits

Subunits Comment Organism
homohexamer 6 * 56000, SDS-PAGE Aspergillus terreus

Synonyms

Synonyms Comment Organism
GedA
-
 Aspergillus terreus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
 Aspergillus terreus