Cloned (Comment) | Organism |
---|---|
- |
Thermoplasma acidophilum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet | Thermoplasma acidophilum | m2G26 and m22G26 are formed by Trm1 | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in prolongator tRNAMet | Thermoplasma acidophilum | m2G26 and m22G26 are formed by Trm1 | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in prolongator tRNAMet | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in tRNA | Thermoplasma acidophilum | G modification at position 26 is a mixture of m2G and m22G generated by Trm1 | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermoplasma acidophilum | - |
- |
- |
Thermoplasma acidophilum | P57706 | - |
- |
Thermoplasma acidophilum HO-62 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Thermoplasma acidophilum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 S-adenosyl-L-methionine + guanine26 in elongator tRNAMet | - |
Thermoplasma acidophilum | 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in elongator tRNAMet | - |
? | |
2 S-adenosyl-L-methionine + guanine26 in elongator tRNAMet | - |
Thermoplasma acidophilum HO-62 | 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in elongator tRNAMet | - |
? | |
2 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet | - |
Thermoplasma acidophilum | 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet | - |
? | |
2 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet | - |
Thermoplasma acidophilum HO-62 | 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet | - |
? | |
2 S-adenosyl-L-methionine + guanine26 in tRNALeu(UAG) | - |
Thermoplasma acidophilum | 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNALeu(UAG) | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet | m2G26 and m22G26 are formed by Trm1 | Thermoplasma acidophilum | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in prolongator tRNAMet | m2G26 and m22G26 are formed by Trm1 | Thermoplasma acidophilum | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in prolongator tRNAMet | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in tRNA | - |
Thermoplasma acidophilum | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA | - |
? | |
4 S-adenosyl-L-methionine + guanine26 in tRNA | G modification at position 26 is a mixture of m2G and m22G generated by Trm1 | Thermoplasma acidophilum | 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA | - |
? | |
additional information | the enzyme Trm1 is single site-specific | Thermoplasma acidophilum | ? | - |
? | |
S-adenosyl-L-methionine + guanine26 in elongator tRNAMet | - |
Thermoplasma acidophilum | S-adenosyl-L-homocysteine + N2-methylguanine26 in elongator tRNAMet | - |
? | |
S-adenosyl-L-methionine + guanine26 in initiator tRNAMet | - |
Thermoplasma acidophilum | S-adenosyl-L-homocysteine + N2-methylguanine26 in initiator tRNAMet | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ta0997 | locus name | Thermoplasma acidophilum |
Trm1 | - |
Thermoplasma acidophilum |
tRNA (guanine(26)-N(2))-dimethyltransferase | - |
Thermoplasma acidophilum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
assay at | Thermoplasma acidophilum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Thermoplasma acidophilum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | - |
Thermoplasma acidophilum |
General Information | Comment | Organism |
---|---|---|
physiological function | initiator tRNAMet from Thermoplasma acidophilum contains the m22G26 modification in addition to m2G26, the TrmI activity is responsible for these modifications | Thermoplasma acidophilum |