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Literature summary for 2.1.1.201 extracted from

  • Rodriguez-Hidalgo, M.; Luna-Sanchez, M.; Hidalgo-Gutierrez, A.; Barriocanal-Casado, E.; Mascaraque, C.; Acuna-Castroviejo, D.; Rivera, M.; Escames, G.; Lopez, L.
    Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis (2018), Sci. Rep., 8, 14013 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus Q9CXI0
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-

Synonyms

Synonyms Comment Organism
COQ5
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Mus musculus

General Information

General Information Comment Organism
physiological function the lack of COQ9 in Coq9Q95X middle-age mutant mice triggers the reduction of COQ7, COQ6 and COQ5, which results in an increase in life expectancy. The hepatic CoQ levels are not decreased and neither mitochondrial dysfunction or increased oxidative stress are observed in liver Mus musculus