Cloned (Comment) | Organism |
---|---|
expressed in Mus musculus liver and kidney | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | GNMT is translocated into nuclei after aflatoxin B1 treatment | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + glycine | - |
Homo sapiens | S-adenosyl-L-homocysteine + N-methylglycine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GNMT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | GNMT is a tumor suppressor for hepatocellular carcinoma cells and it exerts protective effects in hepatocytes via direct interaction with aflatoxin B1, resulting in reduced aflatoxin B1-DNA adducts formation and cell death | Homo sapiens |