Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Streptococcus pneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptococcus pneumoniae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + guanine748 in 23S rRNA | the enzyme methylates 23S rRNA at nucleotide G748, which is situated in a stem-loop (hairpin 35) at the macrolide binding site of the ribosome. Binding of RlmAII methyltransferase induces chemical shift changes in the RNA. The conformation of hairpin 35 that interacts with RlmAII is radically different from the structure this hairpin adopts within the 50S subunit | Streptococcus pneumoniae | S-adenosyl-L-homocysteine + N1-methylguanine748 in 23S rRNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
methyltransferase RlmAII | - |
Streptococcus pneumoniae |
RlmAII | - |
Streptococcus pneumoniae |
TlrB | - |
Streptococcus pneumoniae |