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Literature summary for 2.1.1.183 extracted from
- Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis? (1998), Mol. Cell. Biol., 18, 2360-2370.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleolus | - |
Saccharomyces cerevisiae | 5730 | - |
| nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA | Saccharomyces cerevisiae | isolation of mutations that uncouple the enzymatic function of Dim1p in methylation from its involvement in prerRNA processing | 4 S-adenosyl-L-homocysteine + N6-dimethyladenosine1779/N6-dimethyladenine1780 in 18S rRNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | C7GSG6 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA | - |
Saccharomyces cerevisiae | 4 S-adenosyl-L-homocysteine + N6-dimethyladenine1779/N6-dimethyladenine1780 in 18S rRNA | - |
? | |
| 4 S-adenosyl-L-methionine + adenine1779/adenine1780 in 18S rRNA | isolation of mutations that uncouple the enzymatic function of Dim1p in methylation from its involvement in prerRNA processing | Saccharomyces cerevisiae | 4 S-adenosyl-L-homocysteine + N6-dimethyladenosine1779/N6-dimethyladenine1780 in 18S rRNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 18S rRNA dimethylase Dim1p | - |
Saccharomyces cerevisiae |
| Dim1p | - |
Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | isolation of mutations that uncouple the enzymatic function of Dim1p in methylation from its involvement in prerRNA processing | Saccharomyces cerevisiae |
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