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Literature summary for 2.1.1.182 extracted from

  • Connolly, K.; Rife, J.P.; Culver, G.
    Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA (2008), Mol. Microbiol., 70, 1062-1075.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine KsgA as a possible anti-microbial drug target Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Protein Variants

Protein Variants Comment Organism
E66A catalytically inactive enzyme form Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P06992
-
-

Synonyms

Synonyms Comment Organism
KsgA
-
Escherichia coli

General Information

General Information Comment Organism
malfunction cold sensitivity and altered ribosomal profiles are associated with a DELTAksgA genotype in Escherichia coli Escherichia coli
physiological function KsgA acts as a ribosome biogenesis factor. KsgA alters 16S rRNA processing and has a critical role is as a supervisor of biogenesis of 30S subunits in vivo Escherichia coli