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Literature summary for 2.1.1.179 extracted from

  • Gutierrez, B.; Douthwaite, S.; Gonzalez-Zorn, B.
    Indigenous and acquired modifications in the aminoglycoside binding sites of Pseudomonas aeruginosa rRNAs (2013), RNA Biol., 10, 1324-1332.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.179

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + guanine1405 in 16S rRNA Pseudomonas aeruginosa
-
 S-adenosyl-L-homocysteine + N7-methylguanine1405 in 16S rRNA
-
 ?
S-adenosyl-L-methionine + guanine1405 in 16S rRNA Pseudomonas aeruginosa BB1285
-
 S-adenosyl-L-homocysteine + N7-methylguanine1405 in 16S rRNA
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-
Pseudomonas aeruginosa BB1285
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + guanine1405 in 16S rRNA
-
 Pseudomonas aeruginosa S-adenosyl-L-homocysteine + N7-methylguanine1405 in 16S rRNA
-
 ?
S-adenosyl-L-methionine + guanine1405 in 16S rRNA
-
 Pseudomonas aeruginosa BB1285 S-adenosyl-L-homocysteine + N7-methylguanine1405 in 16S rRNA
-
 ?

Synonyms

Synonyms Comment Organism
RmtD
-
 Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function the enzyme confers high-level resistance to aminoglycosides Pseudomonas aeruginosa