Literature summary for 2.1.1.17 extracted from

Caudill, M.A.; Dellschaft, N.; Solis, C.; Hinkis, S.; Ivanov, A.A.; Nash-Barboza, S.; Randall, K.E.; Jackson, B.; Solomita, G.N.; Vermeylen, F.
Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype (2009), J. Nutr., 139, 727-733.

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Protein Variants

Protein Variants	Comment	Organism
additional information	the A5465G variant form of the PEMT protein is less able to compete for S-adenosyl-L-methionine especially in a folate deplete-environment and is linked to fatty liver disease	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine	-	Homo sapiens	S-adenosyl-L-homocysteine + phosphatidyl-N,N-dimethylethanolamine	-	?

Synonyms

Synonyms	Comment	Organism
PEMT	-	Homo sapiens

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Release 2023.1 (January 2023)