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Literature summary for 2.1.1.17 extracted from

  • Shields, D.J.; Lehner, R.; Agellon, L.B.; Vance, D.E.
    Membrane topography of human phosphatidylethanolamine N-methyltransferase (2003), J. Biol. Chem., 278, 2956-2962.
    View publication on PubMed
Search for more literature for 2.1.1.17

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-
membrane
-
 Homo sapiens 16020
-
membrane topographical model: 4 transmembrane regions span the membrane such that both the N and C termini of the enzyme are localized external to the ER. Two hydrophilic connecting loops protrude into the luminal face of the microsomes whereas a corresponding loop protrudes on the cytosolic side remains proximate to the membrane Homo sapiens 16020
-
membrane mitochondria-associated membrane Homo sapiens 16020
-
mitochondrion
-
 Homo sapiens 5739
-
mitochondrion mitochondria associated membrane Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
 x * 22000, SDS-PAGE, epitope-tagged protein Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + phosphatidylethanolamine
-
 Homo sapiens S-adenosyl-L-homocysteine + phosphatidyl-N-methylethanolamine
-
 ?

Subunits

Subunits Comment Organism
? x * 22000, SDS-PAGE, epitope-tagged protein Homo sapiens
More membrane protein, four transmembrane regions, topographical model Homo sapiens