Literature summary for 2.1.1.164 extracted from

Zhang, C.; Weller, R.L.; Thorson, J.S.; Rajski, S.R.
Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine (2006), J. Am. Chem. Soc., 128, 2760-2761.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4'-demethylrebeccamycin + S-adenosyl-L-methionine	Lentzea aerocolonigenes	-	rebeccamycin + S-adenosyl-L-homocysteine	-	?

Organism

Organism	UniProt	Comment	Textmining
Lentzea aerocolonigenes	Q8KZ94	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4'-demethylrebeccamycin + S-adenosyl-L-methionine	-	Lentzea aerocolonigenes	rebeccamycin + S-adenosyl-L-homocysteine	-	?
dechlorinated 4'-demethyl-rebeccamycin + 5'-[[(3S)-3-amino-3-carboxypropyl](2-iodoethyl)ammonio]-5'-deoxyadenosine	-	Lentzea aerocolonigenes	dechlorinated rebeccamycin + ?	-	?
dechlorinated 4'-demethyl-rebeccamycin + S-adenosyl-L-methionine	-	Lentzea aerocolonigenes	dechlorinated rebeccamycin + S-adenosyl-L-homocysteine	-	?

Synonyms

Synonyms	Comment	Organism
RebM	-	Lentzea aerocolonigenes

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Release 2023.1 (January 2023)