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Literature summary for 2.1.1.157 extracted from

  • Kimura, Y.; Kawasaki, S.; Yoshimoto, H.; Takegawa, K.
    Glycine betaine biosynthesized from glycine provides an osmolyte for cell growth and spore germination during osmotic stress in Myxococcus xanthus (2010), J. Bacteriol., 192, 1467-1470.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.157

Cloned(Commentary)

Cloned (Comment) Organism
gene sdmA, DNA and amino acid sequence determination and analysis, sequence comparison Myxococcus xanthus

Protein Variants

Protein Variants Comment Organism
additional information construction of a chromosomal sdmA gene disruption knockout mutant, phenotype, overview Myxococcus xanthus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
27900
-
 x * 27900, about, sequence calculation Myxococcus xanthus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + N,N-dimethylglycine Myxococcus xanthus
-
 S-adenosyl-L-homocysteine + betaine
-
 ?
S-adenosyl-L-methionine + sarcosine Myxococcus xanthus
-
 S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
 ?

Organism

Organism UniProt Comment Textmining
Myxococcus xanthus
-
 gene smdA encodes a Sdm homologue protein
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + N,N-dimethylglycine
-
 Myxococcus xanthus S-adenosyl-L-homocysteine + betaine
-
 ?
S-adenosyl-L-methionine + sarcosine
-
 Myxococcus xanthus S-adenosyl-L-homocysteine + N,N-dimethylglycine
-
 ?

Subunits

Subunits Comment Organism
? x * 27900, about, sequence calculation Myxococcus xanthus

Synonyms

Synonyms Comment Organism
MXAN 3190
-
 Myxococcus xanthus
sarcosine dimethylglycine methyltransferase
-
 Myxococcus xanthus
Sdm
-
 Myxococcus xanthus
Sdm homologue protein
-
 Myxococcus xanthus
SdmA
-
 Myxococcus xanthus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
 Myxococcus xanthus

General Information

General Information Comment Organism
malfunction disruption of the sdmA gene, encoding Sdm homologue protein, generates a mutant that exhibits a longer lag period of growth and delayed spore germination under osmostress, it shows normal growth in CYE medium at 30°C, phenotype, overview Myxococcus xanthus
metabolism glycine sarcosine methyltransferase, EC 2.1.1.156, and sarcosine dimethylglycine methyltransferase catalyze glycine betaine synthesis from glycine Myxococcus xanthus