Literature summary for 2.1.1.142 extracted from

Zhou, W.; Song, Z.; Liu, J.; Miller, M.B.; Nes, W.D.
24-Thiacycloartanol, a potent mechanism-based inactivator of plant sterol methyltransferase (2004), Tetrahedron Lett., 45, 875-878.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
(3beta24R,S)-24-methyl-24-thionacycloart-3-ol iodide	reversible, non-competitive-type	Glycine max
24-thiacycloartanol	irreversible	Glycine max

Organism

Organism	UniProt	Comment	Textmining
Glycine max	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + cycloartenol	-	Glycine max	S-adenosyl-L-homocysteine + 24(28)methylene cycloartanol	-	?

Synonyms

Synonyms	Comment	Organism
sterol methyltransferase	-	Glycine max

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000055	-	(3beta24R,S)-24-methyl-24-thionacycloart-3-ol iodide	-	Glycine max
0.002	-	24-thiacycloartanol	-	Glycine max

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Release 2023.1 (January 2023)