Organism | UniProt | Comment | Textmining |
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Aspergillus fumigatus | - |
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Synonyms | Comment | Organism |
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FspC | - |
Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
physiological function | fumisoquin biosynthesis requires the N-methyltransferase FsqC and the FAD-dependent oxidase FsqB, which represent functional analogs of coclaurine N-methyltransferase and berberine bridge enzyme in plants. Deletion of the N-methyltransferase FsqC, phenol 2-monooxygenase FsqG, or FAD-dependent oxidase FsqB in a strain overexpressing FsqA leads to complete abolishment of isoquinoline alkaloid production and accumulation of a series of benzyl pyrroles, including fumipyrrole | Aspergillus fumigatus |