Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Papaver somniferum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + (S)-coclaurine | Papaver somniferum | - |
S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Papaver somniferum | Q7XB08 | cv. Marianne, opium poppy | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | sequence comparison | Papaver somniferum | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
phylogenetic analysis reveales a monophyletic clade for (S)-coclaurine N-methyltransferase (CNMT) and (S)-tetrahydroprotoberberine cis-N-methyltransferase (TNMT), 48% identity of amino acid sequence, downstream metabolic role suggests that TNMT derives from gene duplication after more ancient recruitment of CNMT, phylogenetic relationship between CNMT and TNMT provides new insights into evolutionary recruitment of enzymes into plant alkaloid pathways | Papaver somniferum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + (S)-coclaurine | - |
Papaver somniferum | S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine | - |
? | |
S-adenosyl-L-methionine + (S)-coclaurine | analysis of the evolutionary recruitment of enzymes into plant alkaloid pathways | Papaver somniferum | S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(S)-Coclaurine N-methyltransferase | - |
Papaver somniferum |
CNMT | - |
Papaver somniferum |