Protein Variants | Comment | Organism |
---|---|---|
G134A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
G60A | inactive | Homo sapiens |
G80A | inactive | Homo sapiens |
G82A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
I101A | inactive | Homo sapiens |
L160A | inactive | Homo sapiens |
L77A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
N155A | inactive | Homo sapiens |
R57A | the mutant's activity is seriously impaired compared with that of wild type | Homo sapiens |
R83A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
S81A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
T104A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
V157A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
V161A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
Y135A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
Y58A | the mutants activity is seriously impaired compared with that of wild type | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0012 | - |
arsenite | mutant enzyme G134A, at pH 7.0 and 37°C | Homo sapiens | |
0.0018 | - |
arsenite | mutant enzyme R83A, at pH 7.0 and 37°C | Homo sapiens | |
0.0022 | - |
arsenite | mutant enzyme V157A, at pH 7.0 and 37°C | Homo sapiens | |
0.0026 | - |
arsenite | mutant enzyme R57A, at pH 7.0 and 37°C | Homo sapiens | |
0.0027 | - |
arsenite | mutant enzyme S81A, at pH 7.0 and 37°C | Homo sapiens | |
0.0032 | - |
arsenite | wild type enzyme, at pH 7.0 and 37°C | Homo sapiens | |
0.0032 | - |
arsenite | mutant enzyme V161A, at pH 7.0 and 37°C | Homo sapiens | |
0.007 | - |
arsenite | mutant enzyme T104A, at pH 7.0 and 37°C | Homo sapiens | |
0.007 | - |
arsenite | mutant enzyme Y135A, at pH 7.0 and 37°C | Homo sapiens | |
0.0076 | - |
arsenite | mutant enzyme Y58A, at pH 7.0 and 37°C | Homo sapiens | |
0.0087 | - |
arsenite | mutant enzyme G82A, at pH 7.0 and 37°C | Homo sapiens | |
0.0096 | - |
arsenite | mutant enzyme L77A, at pH 7.0 and 37°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + arsenite | Homo sapiens | - |
S-adenosyl-L-homocysteine + methylarsonate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9HBK9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + arsenite | - |
Homo sapiens | S-adenosyl-L-homocysteine + methylarsonate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
arsenic (III) methyltransferase | - |
Homo sapiens |
AS3MT | - |
Homo sapiens |