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Literature summary for 2.1.1.137 extracted from

  • Qin, J.; Rosen, B.P.; Zhang, Y.; Wang, G.; Franke, S.; Rensing, C.
    Arsenic detoxification and evolution of trimethylarsine gas by a microbial arsenite S-adenosylmethionine methyltransferase (2006), Proc. Natl. Acad. Sci. USA, 103, 2075-2080.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
wild-type ArsM and the C281/282S ArsMC2 variant, both with a His6 tag, are expressed in Escherichia coli Rhodopseudomonas palustris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + arsenite Rhodopseudomonas palustris methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic S-adenosyl-L-homocysteine + methylarsonate
-
?
S-adenosyl-L-methionine + arsenite Rhodopseudomonas palustris CGA009 methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic S-adenosyl-L-homocysteine + methylarsonate
-
?

Organism

Organism UniProt Comment Textmining
Rhodopseudomonas palustris
-
-
-
Rhodopseudomonas palustris CGA009
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Rhodopseudomonas palustris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + arsenite methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic Rhodopseudomonas palustris S-adenosyl-L-homocysteine + methylarsonate
-
?
S-adenosyl-L-methionine + arsenite ArsM catalyzes the formation of a number of methylated intermediates from arsenite, with trimethylarsine as the end product Rhodopseudomonas palustris S-adenosyl-L-homocysteine + methylarsonate
-
?
S-adenosyl-L-methionine + arsenite methylation of environmental arsenic by conversion to soluble and gaseous methylated species is a detoxifying process that may contribute to global cycling of arsenic Rhodopseudomonas palustris CGA009 S-adenosyl-L-homocysteine + methylarsonate
-
?
S-adenosyl-L-methionine + arsenite ArsM catalyzes the formation of a number of methylated intermediates from arsenite, with trimethylarsine as the end product Rhodopseudomonas palustris CGA009 S-adenosyl-L-homocysteine + methylarsonate
-
?

Synonyms

Synonyms Comment Organism
ArsM
-
Rhodopseudomonas palustris