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Literature summary for 2.1.1.13 extracted from

  • Koutmos, M.; Pejchal, R.; Bomer, T.M.; Matthews, R.G.; Smith, J.L.; Ludwig, M.L.
    Metal active site elasticity linked to activation of homocysteine in methionine synthases (2008), Proc. Natl. Acad. Sci. USA, 105, 3286-3291.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
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Thermotoga maritima

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, using 25% 1,2-propanediol, 10% (v/v) glycerol, 5% (w/v) PEG 3000, 100 mM potassium citrate, pH 4.8, 15% (v/v) 1,2,3-heptanetriol, and 100 mM YCl3 (final pH, 5.2), at 4°C Thermotoga maritima

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc is coordinated by Cys-207, Cys-272, and Cys-273 Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima
-
-
-

Purification (Commentary)

Purification (Comment) Organism
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Thermotoga maritima

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N5-methyltetrahydropteroylmonoglutamate + L-homocysteine
-
Thermotoga maritima tetrahydropteroylmonoglutamate + L-methionine
-
?

Synonyms

Synonyms Comment Organism
cobalamin-dependent methionine synthase
-
Thermotoga maritima
MetH
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Thermotoga maritima

Cofactor

Cofactor Comment Organism Structure
vitamin B12
-
Thermotoga maritima