BRENDA - Enzyme Database show
show all sequences of 2.1.1.114

Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins

Zhu, Y.; Wu, B.; Zhang, X.; Fan, X.; Niu, L.; Li, X.; Wang, J.; Teng, M.; Biochem. J. 470, 105-114 (2015)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expressed in Escherichia coli BL21(DE3) cells
Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
Homo sapiens
Crystallization (Commentary)
Crystallization
Organism
-
Escherichia coli
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrial membrane
-
Homo sapiens
31966
-
plasma membrane
-
Escherichia coli
5886
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
Homo sapiens
-
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
?
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
Escherichia coli
-
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Escherichia coli
P17993
-
-
Homo sapiens
-
-
-
Purification (Commentary)
Commentary
Organism
Ni-NTA column chromatography and Superdex 200 gel filtration
Escherichia coli
Ni-NTA column chromatography and Superdex 200 gel filtration
Homo sapiens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
-
733306
Homo sapiens
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
-
?
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
-
733306
Escherichia coli
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
-
?
Subunits
Subunits
Commentary
Organism
monomer
x-ray crystallography
Escherichia coli
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in Escherichia coli BL21(DE3) cells
Escherichia coli
expressed in Escherichia coli BL21(DE3) cells
Homo sapiens
Crystallization (Commentary) (protein specific)
Crystallization
Organism
-
Escherichia coli
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrial membrane
-
Homo sapiens
31966
-
plasma membrane
-
Escherichia coli
5886
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
Homo sapiens
-
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
?
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
Escherichia coli
-
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
Ni-NTA column chromatography and Superdex 200 gel filtration
Escherichia coli
Ni-NTA column chromatography and Superdex 200 gel filtration
Homo sapiens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
-
733306
Homo sapiens
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
-
?
S-adenosyl-L-methionine + 3,4-dihydroxy-5-all-trans-polyprenylbenzoate
-
733306
Escherichia coli
S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-5-all-trans-polyprenylbenzoate
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
monomer
x-ray crystallography
Escherichia coli
General Information
General Information
Commentary
Organism
physiological function
the primary role of the enzyme is to serve as an electron carrier in the respiratory electron transport chain in the plasma membrane
Escherichia coli
physiological function
the primary role of the enzyme is to serve as an electron carrier in the respiratory electron transport chain in the mitochondrial inner membrane
Homo sapiens
General Information (protein specific)
General Information
Commentary
Organism
physiological function
the primary role of the enzyme is to serve as an electron carrier in the respiratory electron transport chain in the plasma membrane
Escherichia coli
physiological function
the primary role of the enzyme is to serve as an electron carrier in the respiratory electron transport chain in the mitochondrial inner membrane
Homo sapiens
Other publictions for EC 2.1.1.114
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
733306
Zhu
Structural and biochemical stu ...
Escherichia coli, Homo sapiens
Biochem. J.
470
105-114
2015
-
-
2
1
-
-
-
-
2
-
-
2
-
2
-
-
2
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
-
-
-
-
2
-
-
2
-
-
-
2
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
733930
Gomez
Restoring de novo coenzyme Q b ...
Caenorhabditis elegans, Caenorhabditis elegans N2
Gene
506
106-116
2012
-
-
1
-
-
-
-
-
-
-
-
2
-
18
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
704413
Marbois
Lee, P.T.; Strahan, J.; Shephe ...
Saccharomyces cerevisiae
J. Biol. Chem.
280
20231-20238
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485141
Jonassen
Isolation and functional expre ...
Homo sapiens
J. Biol. Chem.
275
12381-12387
2000
-
-
1
-
-
-
-
-
-
-
1
1
-
1
-
-
-
-
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
1
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485140
Poon
Yeast and rat Coq3 and Escheri ...
Rattus norvegicus, Saccharomyces cerevisiae
J. Biol. Chem.
274
21665-21672
1999
-
-
1
-
-
-
-
-
1
-
-
2
-
8
-
-
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
485139
Avelange-Macheral
Cloning and functional express ...
Arabidopsis thaliana
Plant J.
14
203-213
1998
-
-
1
-
-
-
-
-
3
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
703840
Marbois
Cloning of a rat cDNA encoding ...
Rattus norvegicus
Gene
138
213-217
1994
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
485138
Clarke
Ubiquinone biosynthesis in Sac ...
Saccharomyces cerevisiae
J. Biol. Chem.
266
16636-16644
1991
-
-
1
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-