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Literature summary for 2.1.1.111 extracted from

  • Choo, H.J.; Ahn, J.H.
    Synthesis of three bioactive aromatic compounds by introducing polyketide synthase genes into engineered Escherichia coli (2019), J. Agric. Food Chem., 67, 8581-8589 .
    View publication on PubMed

Application

Application Comment Organism
synthesis production of 4-hydroxycoumarin, 2,4-dihydroxyquinoline, and 4-hydroxy-1-methyl-2(1H)-quinolone in Escherichia coli using genes for the synthesis of salicylic acid from chorismate to supply the substrate for 4-hydroxycoumarin and the gene encoding N-methyltransferase for the synthesis of N-methylanthranilate from anthranilate. 255.4 mg/l 4-hydroxycoumarin, 753.7 mg/l dihydroxyquinoline, and 17.5 mg/l 4-hydroxy-1-methyl-2(1H)-quinolone are synthesized Ruta graveolens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Ruta graveolens

Organism

Organism UniProt Comment Textmining
Ruta graveolens A9X7L0
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