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Literature summary for 2.1.1.107 extracted from

  • Warren, M.J.; Gonzalez, M.D.; Williams, H.J.; Stolowich, N.J.; Scott, A.I.
    Uroporpyrinogen III methylase catalyzes the enzymatic synthesis of sirohydrochlorines II and IV by a clockwise mechanism (1990), J. Am. Chem. Soc., 112, 5343-5345.
No PubMed abstract available
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Cloned(Commentary)

Cloned (Comment) Organism
overexpression of cysG gene Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 S-adenosyl-L-methionine + uroporphyrinogen III Escherichia coli involved in biosynthesis of sirohydrochlorin 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 S-adenosyl-L-methionine + uroporphyrinogen III methylates positions 2 and 7 Escherichia coli 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
2 S-adenosyl-L-methionine + uroporphyrinogen III involved in biosynthesis of sirohydrochlorin Escherichia coli 2 S-adenosyl-L-homocysteine + dihydrosirohydrochlorin + 2 H+ product is precorrin-2 ?
S-adenosyl-L-methionine + uroporphyrinogen I methylates positions 2 and 7 Escherichia coli ?
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