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Literature summary for 2.1.1.100 extracted from

  • Vervacke, J.S.; Funk, A.L.; Wang, Y.C.; Strom, M.; Hrycyna, C.A.; Distefano, M.D.
    Diazirine-containing photoactivatable isoprenoid: synthesis and application in studies with isoprenylcysteine carboxyl methyltransferase (2014), J. Org. Chem., 79, 1971-1978.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.100

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0066
-
 biotin-Peg4-K(5-Fam)YIIKGVFWDPAC(C10-Diazirine)-OH apparent value, at pH 7.5 and 30°C Saccharomyces cerevisiae
0.0122
-
 biotin-Peg4-YIIKGVFWDPAC(Fr)-OH apparent value, at pH 7.5 and 30°C Saccharomyces cerevisiae
0.0159
-
 N-acetyl-S-farnesyl-L-cysteine apparent value, at pH 7.5 and 30°C Saccharomyces cerevisiae
0.0278
-
 biotin-Peg4-K(5-Fam)YIIKGVFWDPAC(C5-m-BP)-OH apparent value, at pH 7.5 and 30°C Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 x * 36000, His-tagged enzyme, SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine Saccharomyces cerevisiae
-
 S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + biotin-Peg4-K(5-Fam)YIIKGVFWDPAC(C10-Diazirine)-OH
-
 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + biotin-Peg4-K(5-Fam)YIIKGVFWDPAC(C5-m-BP)-OH
-
 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + biotin-Peg4-YIIKGVFWDPAC(Fr)-OH
-
 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + N-acetyl-S-farnesyl-L-cysteine
-
 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + N-acetyl-S-farnesyl-L-cysteine methyl ester
-
 ?
S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine
-
 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester
-
 ?

Subunits

Subunits Comment Organism
? x * 36000, His-tagged enzyme, SDS-PAGE Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
Icmt
-
 Saccharomyces cerevisiae
isoprenylcysteine carboxyl methyltransferase
-
 Saccharomyces cerevisiae
Ste14p
-
 Saccharomyces cerevisiae